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d i a l y s i s + p a t i e n t s + w i t h o u t + r e q u i r i n g + i n j e c t i o n s + % 0 a + + + + + + o f + e p o + o r + e s a s % 2 c + a s + w e l l + a s + o n + t h e + c o m p l e t e + p r e c l i n i c a l + p a c k a g e + t h e + % 0 a + + + + + + c o m p a n y + w a s + p a r t i c u l a r l y + e n c o u r a g e d + t h a t + c l e a r a n c e + w a s + r e c e i v e d + w i t h i n + % 0 a + + + + + + t h e + 3 0 - d a y + r e q u i r e d + r e g u l a t o r y + r e s p o n s e + p e r i o d + f r o m + s u b m i s s i o n + o f + t h e + % 0 a + + + + + + i n d + a p p l i c a t i o n + a n d + w i t h o u t + m a j o r + i s s u e s + b e i n g + r a i s e d + m e d g e n i c s + v i e w s + % 0 a + + + + + + t h i s + a s + a n + e a r l y % 2 c + s e c o n d + v a l i d a t i o n + f r o m + a n + i n d e p e n d e n t + c r i t i c a l + r e v i e w + % 0 a + + + + + + i n + t h e + u s + o f + i t s + b i o p u m p + p l a t f o r m + t h e + c o m p a n y + a n n o u n c e d + i n + m a r c h + t h a t + % 0 a + + + + + + t h e + n a t i o n a l + i n s t i t u t e s + o f + h e a l t h % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 9 s + r e c o m b i n a n t + d n a + a d v i s o r y + c o m m i t t e e + % 0 a + + + + + + h a d + g i v e n + p o s i t i v e + r e s p o n s e s + t o + t h e + c o m p a n y % c 3 % a 2 % c 2 % 8 0 % c 2 % 9 9 s + p r i o r + s c i e n t i f i c + a n d + % 0 a + + + + + + c l i n i c a l + d a t a + a n d + i t s + p r o p o s e d + p h a s e + i i b + s t u d y + p r o t o c o l % 0 a + + + + % 0 a + + + + % 0 a + + + + + + t h e + c o m p a n y + b e l i e v e s + e p o d u r e + h a s + t h e + p o t e n t i a l + t o + r e v o l u t i o n i z e + t h e + % 0 a + + + + + + t r e a t m e n t + o f + a n e m i a + b y + s t a b i l i z i n g + h e m o g l o b i n + l e v e l s + w i t h i n + a + s a f e + % 0 a + + + + + + r a n g e + t h i s + a p p r o a c h + i s + d e s i g n e d + t o + k e e p + s e r u m + e p o + l e v e l s + w i t h i n + t h e i r + % 0 a + + + + + + n o r m a l + p h y s i o l o g i c a l + r a n g e + a n d + a v o i d + e x c e s s i v e + l e v e l s + r e s u l t i n g + f r o m + % 0 a + + + + + + b o l u s + e p o + i n j e c t i o n s + t h i s + c o u l d + b e + i m p o r t a n t + i n + i m p r o v i n g + s a f e t y + a n d + % 0 a + + + + + + a d d r e s s i n g + m a r k e t + c o n c e r n s + a b o u t + t h e + e f f e c t s + o f + e x c e s s i v e + l e v e l s + o f + e p o + % 0 a + + + + + + u s e d + i n + t h e + t r e a t m e n t + o f + a n e m i a % 0 a + + + + % 0 a + + + + % 0 a + + + + + + a b o u t + m e d g e n i c s m e d g e n i c s + i s + d e v e l o p i n g + a n d + c o m m e r c i a l i z i n g + % 0 a + + + + + + b i o p u m p % c 3 % a 2 % c 2 % 8 4 % c 2 % a 2 % 2 c + a + p r o p r i e t a r y + t i s s u e - b a s e d + p l a t f o r m + t e c h n o l o g y + f o r + t h e + % 0 a + + + + + + s u s t a i n e d + p r o d u c t i o n + a n d + d e l i v e r y + o f + t h e r a p e u t i c + p r o t e i n s + u s i n g + t h e + % 0 a + + + + + + p a t i e n t % 2 7 s + o w n + s k i n + b i o p s y + f o r + t h e + t r e a t m e n t + o f + a + r a n g e + o f + c h r o n i c + % 0 a + + + + + + d i s e a s e s + i n c l u d i n g + a n e m i a % 2 c + h e p a t i t i s + a n d + h e m o p h i l i a % 2 c + a m o n g + o t h e r s + % 0 a + + + + + + m e d g e n i c s + b e l i e v e s + t h i s + a p p r o a c h + h a s + m u l t i p l e + b e n e f i t s + c o m p a r e d + w i t h + % 0 a + + + + + + c u r r e n t + t r e a t m e n t s % 2 c + w h i c h + i n c l u d e + r e g u l a r + a n d + c o s t l y + i n j e c t i o n s + o f + % 0 a + + + + + + t h e r a p e u t i c + p r o t e i n s % 0 a + + + + % 0 a + + + + % 0 a + + + + + + m e d g e n i c s + h a s + t h r e e + l o n g - a c t i n g + p r o t e i n + t h e r a p y + p r o d u c t s + i n + d e v e l o p m e n t + % 0 a + + + + + + b a s e d + o n + t h i s + t e c h n o l o g y % 3 a % 0 a + + + + % 0 a + + + + % 0 a + + + + + + + + e p o d u r e % c 3 % a 2 % c 2 % 8 4 % c 2 % a 2 + t o + p r o d u c e + a n d + d e l i v e r + e r y t h r o p o i e t i n + f o r + m a n y + m o n t h s + f r o m + a + % 0 a + + + + + + + + s i n g l e + a d m i n i s t r a t i o n % 2 c + h a s + d e m o n s t r a t e d + e l e v a t i o n + a n d + s t a b i l i z a t i o n + o f + % 0 a + + + + + + + + h e m o g l o b i n + l e v e l s + i n + a n e m i c + p a t i e n t s + f o r + s i x + t o + m o r e + t h a n + 3 6 + m o n t h s + i n + % 0 a + + + + + + + + a + p h a s e + i % 2 f i i + d o s e - r a n g i n g + t r i a l % 2 c + a n d + h a s + r e c e i v e d + a p p r o v a l + o f + a + p h a s e + % 0 a + + + + + + + + i i a + t r i a l + i n + d i a l y s i s + p a t i e n t s + d u e + t o + l a u n c h + i n + q 2 + 2 0 1 2 + i n + i s r a e l + a n + % 0 a + + + + + + + + i n v e s t i g a t i o n a l + n e w + d r u g + a p p l i c a t i o n + h a s + b e e n + c l e a r e d + b y + t h e + f d a + t o + % 0 a + + + + + + + + i n i t i a t e + a + p h a s e + i i b + s t u d y + t o + e v a l u a t e + t h e + s a f e t y + a n d + e f f i c a c y + o f + % 0 a + + + + + + + + e p o d u r e + i n + t h e + t r e a t m e n t + o f + a n e m i a + i n + d i a l y s i s + p a t i e n t s + i n + t h e + u s % 0 a + + + + + + % 0 a + + + + + + % 0 a + + + + + + + + i n f r a d u r e % c 3 % a 2 % c 2 % 8 4 % c 2 % a 2 + f o r + s u s t a i n e d + p r o d u c t i o n + a n d + d e l i v e r y + o f + i n t e r f e r o n - 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