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Vitamin E supplements at 400 IU/day associated with increased risk of prostate cancer. |
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Washington Post: The study followed more than 35,533 men 50 or older at 427 sites in the United States, Canada and Puerto Rico. The men were divided into four groups who took daily doses of 400 international units of Vitamin E and 200 micrograms of selenium; Vitamin E and a placebo that looked like selenium; selenium and a placebo that looked like Vitamin E; or two placebos. The recommended daily intake of Vitamin E is about 22 international units.
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Dialysis centres running sans urologists - The Nation, Pakistan |
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The Nation, Pakistan
SIALKOT - The kidney patients have been suffering from great difficulties in the dialysis of their kidneys due to non-availability of any urologist at dialysis units established at Sialkot's both DHQ hospitals namely Govt Allama Iqbal Memorial DHQ
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Higher serum 25-D levels of great importance in fighting off tuberculosis infection. |
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EurekAlert: Researchers next tested serum taken from blood samples in healthy humans with and without sufficient vitamin D and found that the immune response was not triggered in serum with lower vitamin D levels, such as those found in African Americans. But, when adequate vitamin D was added to deficient serum, the immune response was effectively activated. Scientists found that there was an 85 percent reduction of colony-forming tuberculosis bacteria in human macrophage cells that were effectively treated with interferon-? in the presence of sufficient vitamin D.
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Do variants of macrophage inhibitory factor gene account for access infections? |
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EurekAlert: To make their discovery, Calandra and colleagues defined the genetic variations of the MIF gene in a group of children with bacterial sepsis and found that a specific variant of the MIF gene was associated with more severe disease and increased mortality. They also analyzed the transmission of genetic variants of the MIF gene from parents to afflicted children. Results from this family study suggested that one specific variant of the MIF gene protects from meningitis during childhood, while another variant is a risk factor for the development of infection. Considering the existence of a link between variations in the MIF gene, MIF expression, and the development of bacterial sepsis in children, this study data may help identify patients who may benefit from future treatment strategies targeting MIF.
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Activating fetal hemoglobin production in mice reverses sickle cell disease. |
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EurekAlert: Flipping a single molecular switch can reverse illness in a model of sickle cell disease, according to a study by researchers at Children's Hospital Boston and Dana-Farber Cancer Institute. When turned off, the switch, a protein called BCL11A, allows the body to manufacture red blood cells with an alternate form of hemoglobin unaffected by the mutation that causes the disease. The findings – reported online by a research team led by Stuart Orkin, MD, of the Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) in the journal Science on October 13 – provide strong evidence that BCL11A could be a powerful treatment target for a significant global health problem, one that affects between 75,000 and 100,000 people in the United States alone.
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