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Dialysis industry news

Stories from the dialysis comunity across the globe.



Sofosbuvir treatment for hepatitis C gives results comparable to interferon. PDF Print
Health Day News: When the new drug, sofosbuvir, is combined with the medication ribavirin, cure rates are as high as traditional therapy, which pairs ribavirin and pegylated interferon, the researchers say. But patients taking sofosbuvir -- a once-a-day pill -- are spared the severe side effects associated with interferon.

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Drinking beet juice lowers blood pressure by 10 mm Hg. PDF Print
BBC: Drinking 250ml (8oz) cut high blood pressure readings by 10mm of mercury (mmHg) in a study of 15 patients, bringing some into the normal range, the journal Hypertension reports.

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Decellularized kidney scaffolds reseeded with cultured cells produce rudimentary urine. PDF Print
Nature: To regenerate functional tissue, we seeded rat kidney scaffolds with epithelial and endothelial cells and perfused these cell-seeded constructs in a whole-organ bioreactor. The resulting grafts produced rudimentary urine in vitro when perfused through their intrinsic vascular bed. When transplanted in an orthotopic position in rat, the grafts were perfused by the recipient's circulation and produced urine through the ureteral conduit in vivo.

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Caveat physicus: Beall's list of scam open access journals and scientific meetings. PDF Print
NY Times: The prestigious, academically sanctioned conference they had in mind has a slightly different name: Entomology 2013 (without the hyphen). The one they had signed up for featured speakers who were recruited by e-mail, not vetted by leading academics. Those who agreed to appear were later charged a hefty fee for the privilege, and pretty much anyone who paid got a spot on the podium that could be used to pad a résumé.

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Vitamin D deficiency impedes mitochondrial energy metabolism in muscle. PDF Print
EurekAlert: Mitochondria use glucose and oxygen to make energy in a form that can be used to run the cell - an energy-rich molecule called ATP. Muscle cells need large amounts of ATP for movement and they use phosphocreatine as a ready and available energy source to make ATP. The mitochondria also replenish this phosphocreatine store after muscle contraction and measuring the time taken to replenish these stores is a measure of mitochondrial efficiency: better mitochondrial function is associated with shorter phosphocreatine recovery times. The team found that these recovery rates significantly improved after the patients took a fixed dose of oral vitamin D for 10-12 weeks. The average phosphocreatine recovery half time decreased from 34.4 sec to 27.8 sec. All patients reported an improvement in symptoms of fatigue after having taken the supplements. In a parallel study, the group demonstrated that low Vitamin D levels were associated with reduced mitochondrial function.

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