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Stories from the dialysis comunity across the globe.
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KDIGO publishes 2012 practice guidelines for treating glomerulonephritis. |
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KDIGO: KDIGO Clinical Practice Guideline for Glomerulonephritis (GN)...Download complete GN Guideline in English (PDF)............. Download Supplementary Materials: Online Appendices 1-3 (PDF).............. Download Supplementary Tables (PDF).......................In citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes (KDIGO) Glomerulonephritis Work Group. KDIGO Clinical Practice Guideline for Glomerulonephritis. Kidney Int, Suppl. 2012; 2: 139–274.
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FDA issues warning about use of high total base content hemodialysis solutions. |
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FDA: Health care providers should review the dialysate acid concentrate labeling for the specific concentrate that they prescribe to determine the components that can contribute to the patient’s overall bicarbonate levels. The levels of acetate, citrate and/or acetic acid vary by formulation and by manufacturer. Be aware that metabolic alkalosis (pre-dialysis serum bicarbonate levels > or = to 27 mEq/L) has been associated with a higher risk of death in hemodialysis patients.
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Intensive glucose control in diabetes does not retard CKD progression (meta-analysis). |
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EurekAlert: To test the hypothesis that aggressive glycemic control can prevent renal disease in patients with type 2 diabetes mellitus, first author Steven G. Coca of Yale and colleagues searched available medical literature and evaluated seven randomized trials involving 28,065 adult patients who were monitored for two to 15 years. The team found that compared with those who had usual treatment, intensively controlling glucose with higher doses of medication did not definitively reduce the risk of impaired kidney function, the need for dialysis, or death from kidney disease.
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Naturally occurring calcium isotope ratios in urine can detect early bone loss. |
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EurekAlert: With the new technique, bone loss is detected by carefully analyzing the isotopes of the chemical element calcium that are naturally present in urine. Isotopes are atoms of an element that differ in their masses. Patients do not need to ingest any artificial tracers and are not exposed to any radiation, so there is virtually no risk, the authors noted.
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AUF1 gene plays central role in aging, inflammation, and cancer. |
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EurekAlert: Researchers at NYU School of Medicine have, for the first time, identified a single gene that simultaneously controls inflammation, accelerated aging and cancer. "This was certainly an unexpected finding," said principal investigator Robert J. Schneider, PhD, the Albert Sabin Professor of Molecular Pathogenesis, associate director for translational research and co-director of the Breast Cancer Program at NYU Langone Medical Center. "It is rather uncommon for one gene to have two very different and very significant functions that tie together control of aging and inflammation. The two, if not regulated properly, can eventually lead to cancer development. It's an exciting scientific find."
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