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Stories from the dialysis comunity across the globe.



Acute kidney injury Activated protein C protective in IRI - Nature.com PDF Print

Acute kidney injury Activated protein C protective in IRI
Nature.com
The anticoagulant serine protease activated protein C (aPC) provides nephroprotection against ischaemia–reperfusion injury (IRI) by maintaining stability of the cold-shock protein YB-1, according to new research. “Within our study we identify a novel ...

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Activation of JAK3/STAT6 contributes to the development of renal fibrosis - Nature.com PDF Print

Activation of JAK3/STAT6 contributes to the development of renal fibrosis
Nature.com
Bone marrow-derived fibroblast precursors (fibrocytes) contribute to the pathogenesis of renal fibrosis, but the mechanisms that underlie their activation and recruitment to the kidney are not fully understood. Now, data from Jingyin Yan and colleagues ...

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Donation to help dialysis patients - Waikato Times PDF Print

Donation to help dialysis patients - Waikato Times Morrinsville Lions Club members chop firewood to raise funds for a modified van for dialysis patients. Photo: SUPPLIED Dialysis patients will soon be able to take a much needed holiday after a $110,000 donation towards a modified campervan.The Morrinsville Lions Club donated $110,000 to the Regional Renal Centre for a $150,000 modified van to help those on dialysis become more mobile.For many long-term dialysis patients, the campervan will give them and their families an opportunity to go away within New Zealand and still be able to access treatment. Donation to help dialysis patients - Waikato Times Supplied/Waikato DHB Morrinsville Lions Club treasurer Bryan Barker, left, hands over a cheque for $110,000 to Waikato DHB clinical director Dr Peter Sizeland, with Waikato DHB clinical nurse manager Nicky Hagan and Lions Club member Hugh Makgill. Regional Renal Centre secretary Angela Eccles said the modified van was really about quality of life and improving many patients' mental health."For some patients they are hooked up to machines for six to eight hours every second day, this will at least give them the opportunity to still get that treatment but enjoy some time away from the hospital or home setting," she said.The van, an eight-seater Mercedes, will be stripped out and refitted as a campervan, complete with dialysis machine, which will used by patients with kidney damage or failure.Morrinsville Lions Club secretary Bryan Barker said this would allow dialysis patients to get away for a few days for a nominal fee. "When you see what these patients have to put up with, this is a very important project, " he said."The opportunity for dialysis patients to go away for even three days is a major exercise as those that have to go the hospital (for treatment) have to make arrangements for treatment at other locations, which is very difficult."With the club's donation, the van could now be purchased and modifications started while Lions continued to raise the rest of the funds, he said. It was hoped the van would be ready in July or August, he said.The funds were raised from donations, trust grants and club fundraisers.About 30 Lions club members cut firewood on a Morrinsville farm to sell, raising a total of $13,000 toward the project.There were also many donations from  Lions clubs throughout the Waikato, King Country and Bay of Plenty districts, he said.  - Stuff Next Hamiltons 150th story:

Operatic hosts massive garage sale

Waikato Times Homepage

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Nephrology fellowship approved for Marshall School of Medicine - HNN Huntingtonnews.net PDF Print

 

Nephrology is a subspecialty of medicine that deals with the physiology and diseases of the kidneys and hypertension.

 

“Expanding our training opportunities to include nephrology is an important step for us as an academic medical center,” said Joseph I. Shapiro, M.D., dean of the school of medicine and a fellowship-trained nephrologist. “This program helps us to increase the number of nephrologists for our region, which suffers from significantly higher rates of chronic kidney disease and hypertension than most other regions of the country.”

  

The new fellowship program, scheduled to begin July 1, 2016, was approved to accept up to four fellows. The two-year nephrology fellowship is completed after a three-year internal medicine residency.

 

“This program is designed to train physicians to become outstanding nephrologists who can serve patients in our region as well as across the United States,” said Paulette S. Wehner, M.D., vice dean for graduate medical education and a professor of cardiology.  “There have been many people involved in the successful accreditation including Drs. Zeid Khitan and Neha Garg, nephrologists in our department of internal medicine, Amanda Jones, program administrator, and Cindy Dailey, director of graduate medical education.”

 

Zeid Khitan, M.D., who will serve as the fellowship program director, says he’s excited to begin.

 

“We are all looking forward to starting a state-of-the-art kidney disease fellowship program aimed at training our candidates to be successful clinicians and scientists,” Khitan said. 

 

With the addition of the new nephrology fellowship, Marshall now has a total of eight ACGME-accredited residency programs and six accredited fellowship programs. 

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High n-3 PUFA Intake Improves Survival After Kidney Transplantation - Renal and Urology News PDF Print
June 15, 2015 High n-3 PUFA Intake Improves Survival After Kidney Transplantation - Renal and Urology News
Highest versus lowest intake associated with a 67% and 88% lower risk of all-cause and cardiovascular mortality, respectively.

Renal transplantrecipients may benefit from marine n-3 polyunsaturated fatty acids (PUFAs) in terms of reduced overall and cardiovascular mortality risk, according to a new study.

Ivar A. Eide, MD, of Oslo University Hospital in Norway, and colleagues conducted an observational cohort study of 1,990 Norwegian recipients of a renal transplant. The investigators measured the marine n-3 PUFA levels in plasma phospholipids using gas chromatography 10 weeks after transplantation. Of the 1,990 patients, 406 (20.4%) died during a median follow-up period of 6.8 years.

Compared with patients in the bottom quartile of PUFA level, those in the top quartile had a significant 67% and 88% lower risk of all-cause and cardiovascular mortality, respectively, in a fully adjusted model. Dr. Eide's team reported online ahead of print in the Clinical Journal of the American Society of Nephrology. In addition, patients in the top quartile had a significant 93% lower risk of sudden cardiac death and a significant 92% lower risk of stroke-related death.

The study had a number of strengths, the most important of which, according to the investigators, was the use of gas chromatography to measure individual plasma phospholipid fatty acids, “which in contrast to dietary questionnaires, correlates very well with actual marine n-3 PUFA intake.” Study limitations include a lack of dietary data to adjust for the full matrix of nutrients and the fact that the researchers performed only a single measurement of plasma phospholipid marine n-3 PUFAs.

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