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DOSE trial published: How to give IV diuretics in acute HF - TheHeart.Org PDF Print
TheHeart.Org
All that may have come at the cost of worsening renal function: more high-dose than low-dose patients showed a jump in serum creatinine to >0.3 mg/dL at any time in the first 72 hours of therapy, a secondary but prespecified safety end point.

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