Modifying Treg cells allows transplantation of human skin onto mice. PDF Print
EurekAlert: Using a humanised mouse, where a mouse lacking its own immune system was given human effector cells and Tregs, the team were able to test the ability of these "specific" Tregs to prevent rejection of human skin grafted onto the mouse. The team found that the "specific" Tregs were significantly more potent than non-specific Tregs (those able to inhibit all effector cells) in protecting skin grafts from immune damage.

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