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Anti–Vascular Endothelial Growth Factor Therapy and Renal Thrombotic ... - Archives of Ophthalmology |
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Archives of Ophthalmology To show that local reduction of VEGF within the kidney is sufficient to trigger the pathogenesis of thrombotic microangiopathy, we used conditional gene targeting to delete VEGF from renal podocytes in adult mice; this resulted in a profound thrombotic |