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Janssen Research Development Submits Application to U.S. FDA for XARELTO ... - PR Newswire (press release) |
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PR Newswire (press release) Patients with renal impairment taking P-gp and weak to moderate CYP3A4 inhibitors may have significant increases in exposure, which may increase bleeding risk. Nonvalvular Atrial Fibrillation: For patients with CrCl 15 mL/min to 50 mL/min, |