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Stories from the dialysis comunity across the globe.
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Large meta-analysis exonerates saturated fat in terms of elevated CV risk. |
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Reuters: When Chowdhury and his team analyzed data on fatty acid intake, they found that none of the types of saturated or polyunsaturated fats had a significant impact on heart disease risk. However, consumption of trans fat - found in some processed foods and some forms of stick margarine - was tied to a 16 percent increase in risk. Guidelines call for avoiding trans fats altogether. When the researchers examined markers of fatty acids in the blood, they also found little difference in heart risk based on levels of saturated or polyunsaturated fats. But the results varied for individual fatty acids.
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Oxadiazoles make up a new class of antibiotics effective against MRSA. |
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EurekAlert: The new class, called oxadiazoles, was discovered in silico (by computer) screening and has shown promise in the treatment of MRSA in mouse models of infection. Researchers who screened 1.2 million compounds found that the oxadiazole inhibits a penicillin-binding protein, PBP2a, and the biosynthesis of the cell wall that enables MRSA to resist other drugs. The oxadiazoles are also effective when taken orally. This is an important feature as there is only one marketed antibiotic for MRSA that can be taken orally.
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ITPA gene variants markedly affect risk of recurrence of hepatitis C after treatment. |
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Sahlgrenska Academy: Martin Lagging and co-workers at the Sahlgrenska Academy have studied an enzyme called inosine trifosfatas (ITPase), which normally prevents the incorporation of defective building blocks into RNA and DNA. Unexpectedly they found that the gene encoding for ITPase (ITPA) had significance for the treatment outcome in chronic hepatitis C virus infection.
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Some NSAIDs found to have weak antibacterial activity. |
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EurekAlert: Some commonly used drugs that combat aches and pains, fever, and inflammation are also thought to have the ability to kill bacteria. New research appearing online on March 13 in the Cell Press journal Chemistry & Biology reveals that these drugs, better known as NSAIDs, act on bacteria in a way that is fundamentally different from current antibiotics. The discovery could open up new strategies for fighting drug-resistant infections and "superbugs."
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Smartphones used to take images of the eye for sharing with health providers. |
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EurekAlert: Researchers at the Stanford University School of Medicine have developed two inexpensive adapters that enable a smartphone to capture high-quality images of the front and back of the eye. The adapters make it easy for anyone with minimal training to take a picture of the eye and share it securely with other health practitioners or store it in the patient's electronic record. "Think Instagram for the eye," said one of the developers, assistant professor of ophthalmology Robert Chang, MD.
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