Global Dialysis

Dialysis industry news

Stories from the dialysis comunity across the globe.

New device informs treatment of sleep apnea.

EurekAlert: Implantation of a sleep apnea device called Inspire® Upper Airway Stimulation (UAS) therapy can lead to significant improvements for patients with obstructive sleep apnea (OSA), according to a study published today in the New England Journal of Medicine. After one year, patients using the device had an approximately 70 percent reduction in sleep apnea severity, as well as significant reductions in daytime sleepiness.

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Potential rewrite of human research guidelines will facilitate database studies.

Institute of Medicine: To first determine if research activities fall within the scope of the Common Rule, the report recommends that HHS define “human subjects research” as a systematic investigation designed to develop or contribute to generalizable knowledge that involves direct interaction or intervention with a living individual or that involves obtaining identifiable private information about an individual. Only research that fits this definition should be subject to IRB procedures and the Common Rule.

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ZS Pharma announces positive results from extended treatment results of hyperkalemia drug.

ZS Pharma: ZS003 Phase 3 Top-Line Results. Top-line results from the Extended Treatment Phase showed that ZS-9 was able to maintain a statistically significant reduction in serum potassium relative to placebo in patients over 12 days of once-daily dosing. .............................. • The trial met the Extended Treatment Phase endpoint at the 5g and 10g doses compared with placebo (P-values of 0.0075, and <0.0001, respectively). ......................................... • ZS-9 was well-tolerated at all doses tested. Overall adverse event and GI adverse event rates and severities were comparable between the placebo and ZS-9 treated patients.

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Portable retinal scanner developed for early detection of eye disease.

OSA: A new optical device puts the power to detect eye disease in the palm of a hand. The tool—about the size of a hand-held video camera—scans a patient’s entire retina in seconds and could aid primary care physicians in the early detection of a host of retinal diseases including diabetic retinopathy, glaucoma and macular degeneration.

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Staph stopper vaccine developed at U. Iowa

U Iowa: Using an animal model that closely resembles human staph infection, the researchers showed that vaccination against three staph toxins provided almost complete protection against staph infections. The vaccinated animals were protected from disease even when they were infected with very high doses of bacteria. Furthermore, not only did the vaccine protect the animals from dying, but seven days after vaccination there were no disease-causing bacteria remaining in the animals' lungs.

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